Abstract: The paper questions the nature of inter-business collaboration in tourism and assesses critically perspectives that seem to take for granted that greater collaboration is necessarily beneficial to tourism destination systems, as well as the businesses within them. It survey some specific strands of relevant literature to argue that such views are often implicit in generic policy or management recommendations regarding tourism governance. In contrast, argues for the need to recognize explicitly the opportunity costs encountered by tourism firms when choosing inter-firm linkages (as well as private-public partnerships) as the latter are embedded in business learning strategies, and reflect a large and diverse set of costs and benefits arising from those choices. The paper appraises the findings from Tremblay and Wegner (2009) exploratory survey of remote tourism businesses in the light of those claims, to show the diversity of perceptions regarding the nature of those costs and benefits emanating from business respondents, and highlights the role of location, business size and functional outlook in shaping those perceptions.