Reduced middle ear infection with non-typeable Haemophilus influenzae, but not Streptococcus pneumoniae, after transition to 10-valent pneumococcal non-typeable H. influenzae protein D conjugate vaccine

Reduced middle ear infection with non-typeable Haemophilus influenzae, but not Streptococcus pneumoniae, after transition to 10-valent pneumococcal non-typeable H. influenzae protein D conjugate vaccine Journal Article

BMC Pediatrics

• Author(s): Leach, Amanda Jane, Wigger, Christine, Hare, Kim, Hampton, Vanya, Beissbarth, Jemima, Andrews, Ross, Chatfield, Mark, Smith-Vaughan, Heidi, Morris, Peter Stanley
• Published: 2015
• Volume: 15
• ISBN: 1471-2431

Link to resource Report broken link

Abstract: In October 2009, 7-valent pneumococcal conjugate vaccine (PCV7: PrevenarTM Pfizer) was replaced in the Northern Territory childhood vaccination schedule by 10-valent pneumococcal Haemophilus influenzae protein D conjugate vaccine (PHiD-CV10; Synflorix™ GlaxoSmithKline Vaccines). This analysis aims to determine whether the reduced prevalence of suppurative otitis media measured in the PHiD-CV10 era was associated with changes in nasopharyngeal (NP) carriage and middle ear discharge (ED) microbiology in vaccinated Indigenous children.

• Urls: https://doi.org/10.1186/s12887-015-0483-8